Anti-RIMS4抗体-抗体-抗体-生物在线
Anti-RIMS4抗体

Anti-RIMS4抗体

商家询价

产品名称: Anti-RIMS4抗体

英文名称: RIMS4

产品编号: YB--11360R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

上海钰博生物科技有限公司
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 Anti-RIMS4抗体

产品编号 YB-11360R
英文名称 RIMS4
中文名称 神经元突触膜胞外分泌调节蛋白4抗体
别    名 C20orf190; dJ781B1.3; Rab3-interacting molecule 4; regulating synaptic membrane exocytosis 4; Regulating synaptic membrane exocytosis protein 4; RIM 4; RIM4 gamma; Rims4; RIMS4_HUMAN.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  神经生物学  细胞类型标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RIMS4:1-100/269 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Rim4 (Rab 3 interacting molecule 4), also known as Rim4 or regulating synaptic membrane exocytosis protein 4, is a 269 amino acid protein that localizes to the cell junction and regulates synaptic membrane exocytosis. Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis. Rab 3 functions in an inhibitory capacity by controlling the recruitment of secretory vesicles into a releasable pool at the plasma membrane. Rim (Rab 3 interacting molecule), a putative effector protein for Rab 3 proteins, is thought to regulate neutrotransmitter release through its interaction with Rab 3 and other synaptic proteins.

Function:
Regulates synaptic membrane exocytosis.

Subunit:
Binds PPFIA3 (By similarity). Does not bind RAB3.

Subcellular Location:
Cell junction; synapse.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 1 C2 domain.

SWISS:
Q9H426

Gene ID:
140730

Database links:

Entrez Gene: 140730 Human

Entrez Gene: 241770 Mouse

Entrez Gene: 266976 Rat

Omim: 611601 Human

SwissProt: Q9H426 Human

SwissProt: P60191 Mouse

SwissProt: Q8CIX1 Rat

Unigene: 517065 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications