MYO1A polyclonal antibody (A01)
产品名称： MYO1A polyclonal antibody (A01)
英文名称： MYO1A polyclonal antibody (A01)
产品编号： H00004640-A01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant MYO1A.
- Immunogen:
- MYO1A (NP_005370, 944 a.a. ~ 1043 a.a) partial recombinant protein with GST tag.
- Sequence:
- SVTSLKDGLFSLHLSEMSSVGSKGDFLLVSEHVIELLTKMYRAVLDATQRQLTVTVTEKFSVRFKENSVAVKVVQGPAGGDNSKLRYKKKGSHCLEVTVQ
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
- MSDS:
Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 4640
- GeneBank Accession#:
- NM_005379
- Protein Accession#:
- NP_005370
- Gene Name:
- MYO1A
- Gene Alias:
- BBMI,DFNA48,MIHC,MYHL
- Gene Description:
- myosin IA
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the myosin superfamily. Myosins are molecular motors that, upon interaction with actin filaments, utilize energy from ATP hydrolysis to generate mechanical force. Each myosin has a conserved N-terminal motor domain that contains both ATP-binding and actin-binding sequences. Following the motor domain is a light-chain-binding 'neck' region containing 1-6 copies of a repeat element, the IQ motif, that serves as a binding site for calmodulin or other members of the EF-hand superfamily of calcium-binding proteins. At the C-terminus, each myosin class has a distinct tail domain that serves in dimerization, membrane binding, protein binding, and/or enzymatic activities and targets each myosin to its particular subcellular location. The kidney epithelial cell line, LLC-PK1-CL4 (CL4), forms a well ordered brush border (BB) on its apical surface. Experiments indicate that the brush border population of the encoded protein turns over rapidly, while its head and tail domains interact transiently with the core actin and plasma membrane, respectively. A rapidly exchanging pool of the protein encoded by this gene envelops an actin core bundle that, by comparison, is static in structure. [provided by RefSeq
- Other Designations:
- brush border myosin-I,deafness, autosomal dominant 48,myosin I heavy chain,myosin, heavy polypeptide-like (100kD)
- Related Disease